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Image Search Results
Journal: bioRxiv
Article Title: Orally Delivered dsRNA-Derived siRNAs Reach the Central Nervous System in Leptinotarsa decemlineata
doi: 10.64898/2026.03.11.711085
Figure Lengend Snippet: (a) Length distribution of RISC-associated small RNAs recovered from the CNS 24 h after dsmGFP exposure, showing a dominant 21-nt siRNA peak. (b) Strand-specific mapping of 21-nt siRNAs from the CNS sample onto the dsmGFP template, revealing a major antisense hotspot similar to that observed in CPB tissues. (c) Length distribution of RISC-bound small RNAs from the remaining tissues, demonstrating a tissue-specific shift to a predominant 22-nt siRNA population. (d) Strand-specific mapping of 22-nt siRNAs from the remaining tissues sample, showing relocation of the dominant antisense hotspot to a secondary region of the dsmGFP sequence.
Article Snippet: Libraries from purified small RNAs (∼500 ng RNA per sample) were prepared using the
Techniques: Sequencing